abstract：PURPOSE:The aim of this study was to investigate the feasibility of assessing dopamine transporter binding after treatment with methylphenidate in the rat using a recently developed high-resolution small animal single-photon emission computed tomograph (TierSPECT) and [123I]FP-CIT. METHODS:[123I]FP-CIT was administere...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Nikolaus S,Wirrwar A,Antke C,Arkian S,Schramm N,Müller HW,Larisch R

更新日期：2005-03-01 00:00:00

abstract：PURPOSE:Dual-isotope simultaneous acquisition single-photon emission computed tomography (DISA SPECT) with 18F-fluorodeoxyglucose (FDG) and (99m)Tc-sestamibi appears attractive for the detection of viable myocardium because it permits simultaneous assessment of glucose utilisation and perfusion. Another potential benef...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Matsunari I,Kanayama S,Yoneyama T,Matsudaira M,Nakajima K,Taki J,Nekolla SG,Tonami N,Hisada K

更新日期：2005-02-01 00:00:00

abstract：:The Annual Congress of the European Association of Nuclear Medicine represents the major scientific and professional event in the field of nuclear medicine in Europe. Specialists from all allied professions meet to discuss the latest findings and discoveries. A very large industrial exhibition demonstrates the latest ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ell PJ,European Association of Nuclear Medicine.

更新日期：2005-01-01 00:00:00

abstract：PURPOSE:The future significance of peptide radiopharmaceuticals in diagnostic imaging with PET will be dependent on methodological aspects, as well as other requirements such as availability of the radionuclide and cost-effectiveness of its production. The aim of this study was to evaluate whether recent improvements i...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Henriksen G,Schottelius M,Poethko T,Hauser A,Wolf I,Schwaiger M,Wester HJ

更新日期：2004-12-01 00:00:00

abstract：PURPOSE:The purpose of this study was to evaluate the impact of [18F]fluorodeoxy-D-glucose positron emission tomography (FDG-PET) on the primary staging of patients with small-cell lung cancer (SCLC). METHODS:FDG-PET was performed in 120 consecutive patients with SCLC during primary staging. In addition, brain examina...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Brink I,Schumacher T,Mix M,Ruhland S,Stoelben E,Digel W,Henke M,Ghanem N,Moser E,Nitzsche EU

更新日期：2004-12-01 00:00:00

abstract：PURPOSE:Right ventricular (RV) performance is known to have prognostic value in patients with congestive heart failure (CHF). Cardiac resynchronization therapy (CRT) has been found to enhance left ventricular (LV) energetics and metabolic reserve in patients with heart failure. The interplay between the LV and RV may p...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Knuuti J,Sundell J,Naum A,Engblom E,Koistinen J,Ylitalo A,Stolen KQ,Kalliokoski R,Nekolla SG,Bax KE,Airaksinen KE

更新日期：2004-12-01 00:00:00

abstract：PURPOSE:The aim of the study was to determine the accuracy of non-rigid nine-parameter image registrations based on 153Gd transmission computed tomography (TCT) images as compared with those based on 99mTc-ethyl cysteinate dimer (ECD) images and to assess whether normalised mutual information (NMI) or count difference ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Jacobs F,Koole M,Goethals I,Van de Wiele C,Ham H,Dierckx R

更新日期：2004-11-01 00:00:00

abstract：:[Yttrium-90-DOTA-Tyr(3)]-octreotide (DOTATOC) and [(177)Lu-DOTA-Tyr(3)-Thr(8)]-octreotide (DOTATATE) are used for peptide receptor-mediated radionuclide therapy (PRMRT) in neuroendocrine tumours. No human data comparing these two compounds are available so far. We used (111)In as a surrogate for (90)Y and (177)Lu and ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Forrer F,Uusijärvi H,Waldherr C,Cremonesi M,Bernhardt P,Mueller-Brand J,Maecke HR

更新日期：2004-09-01 00:00:00

abstract：:We assessed the accuracy of brain perfusion single-photon emission computed tomography (SPECT) in discriminating between patients with probable Alzheimer's disease (AD) at the very early stage and age-matched controls before and after partial volume correction (PVC). Three-dimensional MRI was used for PVC. We randomly...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kanetaka H,Matsuda H,Asada T,Ohnishi T,Yamashita F,Imabayashi E,Tanaka F,Nakano S,Takasaki M

更新日期：2004-07-01 00:00:00

abstract：:In prostate cancer, confirmation of metastatic involvement of the skeleton has traditionally been achieved by bone scintigraphy, although the widespread availability of prostate-specific antigen (PSA) measurements has tended to eliminate the need for this investigation. The potential of bone scintigraphy to predict sk...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Soerdjbalie-Maikoe V,Pelger RC,Lycklama à Nijeholt GA,Arndt JW,Zwinderman AH,Bril H,Papapoulos SE,Hamdy NA

更新日期：2004-07-01 00:00:00

abstract：:When projection data are incomplete for various technical reasons, artefacts may occur in the reconstructed images. This study examines whether an iterative reconstruction method, the ordered subsets implementation of the EM algorithm (OSEM), can improve reconstruction and minimise the artefacts compared to filtered b...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hatton RL,Hutton BF,Angelides S,Choong KK,Larcos G

更新日期：2004-06-01 00:00:00

abstract：:Characterisation of the physical performance of the new integrated PET/CT system Discovery ST (GE Medical Systems) has been performed following the NEMA NU 2-1994 (N-94) and the NEMA NU 2-2001 (N-01) standards in both 2D and 3D acquisition configuration. The Discovery ST combines a four or eight multi-slice helical CT...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bettinardi V,Danna M,Savi A,Lecchi M,Castiglioni I,Gilardi MC,Bammer H,Lucignani G,Fazio F

更新日期：2004-06-01 00:00:00

abstract：:Breast cancer is associated with increased glucose consumption and can therefore be visualised with the glucose analogue [(18)F]2-deoxy-2-fluoro-D-glucose (FDG) and positron emission tomography (PET). FDG uptake in the primary tumour can vary substantially, and specific tumour characteristics have been demonstrated to...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Buck AK,Schirrmeister H,Mattfeldt T,Reske SN

更新日期：2004-06-01 00:00:00

abstract：:Transmission measurement is recommended in order to accurately correct for attenuation in myocardial single-photon emission tomography (SPET) studies. It is important that transmission studies are artefact-free, otherwise the attenuation-corrected SPET studies may also be affected. An assumption in transmission studie...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Evans SG,Hutton BF

更新日期：2004-05-01 00:00:00

abstract：:This study demonstrates high-efficiency sterilisation of single cancer cells in a SCID mouse model of leukaemia using rituximab, a monoclonal antibody that targets CD20, labelled with terbium-149, an alpha-emitting radionuclide. Radio-immunotherapy with 5.5 MBq labelled antibody conjugate (1.11 GBq/mg) 2 days after an...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Beyer GJ,Miederer M,Vranjes-Durić S,Comor JJ,Künzi G,Hartley O,Senekowitsch-Schmidtke R,Soloviev D,Buchegger F

更新日期：2004-04-01 00:00:00

abstract：:This review presents neuroimaging studies which have explored the functional anatomy of a variety of cognitive processes represented by the prefrontal cortex (PFC). Overall, these studies have demonstrated that standard prefrontal neuroactivation tasks recruit a widely distributed network within the brain of which the...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Goethals I,Audenaert K,Van de Wiele C,Dierckx R

更新日期：2004-03-01 00:00:00

abstract：:This review summarises the evidence for the role of myocardial perfusion scintigraphy (MPS) in patients with known or suspected coronary artery disease. It is the product of a consensus conference organised by the British Cardiac Society, the British Nuclear Cardiology Society and the British Nuclear Medicine Society ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Underwood SR,Anagnostopoulos C,Cerqueira M,Ell PJ,Flint EJ,Harbinson M,Kelion AD,Al-Mohammad A,Prvulovich EM,Shaw LJ,Tweddel AC,British Cardiac Society.,British Nuclear Cardiology Society.,British Nuclear Medicine Society.,Ro

更新日期：2004-02-01 00:00:00

abstract：:The aims of this study were to assess the potential of fluorine-18 fluorodeoxyglucose positron emission tomography (FDG PET) for tumor grading in chondrosarcoma patients and to evaluate the role of standardized uptake value (SUV) as a parameter for prediction of patient outcome. FDG PET imaging was performed in 31 pat...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Brenner W,Conrad EU,Eary JF

更新日期：2004-02-01 00:00:00

abstract：:Flow quantitation with nitrogen-13 ammonia ((13)NH(3)) and positron emission tomography (PET) is dependent on an accurate blood time-activity curve. This is conveniently derived from the PET images by drawing a region of interest in the left ventricular cavity. The blood time-activity curve obtained in this way, howev...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hove JD,Iida H,Kofoed KF,Freiberg J,Holm S,Kelbaek H

更新日期：2004-01-01 00:00:00

abstract：:As measurement of glomerular filtration rate (GFR) is now generally the responsibility of departments of nuclear medicine, it is important for nuclear medicine physicians and scientists to understand the pharmacokinetics of the indicators and radiotracers that are used, generally known as filtration markers. The singl...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Peters AM

更新日期：2004-01-01 00:00:00

abstract：:This study was performed to prospectively investigate the impact of image fusion in resolving discrepant findings between fluorine-18 fluorodeoxyglucose positron emission tomography (FDG-PET) and magnetic resonance imaging (MRI) or X-ray computed tomography (CT) in patients with gynaecological cancers. Discrepant find...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Tsai CC,Tsai CS,Ng KK,Lai CH,Hsueh S,Kao PF,Chang TC,Hong JH,Yen TC

更新日期：2003-12-01 00:00:00

abstract：:This review describes the properties of available and emerging radiation detector and read-out technologies and discusses how they may affect PET scanner performance. After a general introduction, there is a section in which the physical properties of several different detector scintillators are compared. This is foll...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Humm JL,Rosenfeld A,Del Guerra A

更新日期：2003-11-01 00:00:00

abstract：:The aim of this study was to determine the yield of attenuation correction in myocardial perfusion imaging (MPI), before and after a 1-year experience period. In 48 consecutive patients referred for MPI, both non-corrected (NC) and attenuation-corrected (AC) images were analysed by three independent readers shortly af...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Slart RH,Que TH,van Veldhuisen DJ,Poot L,Blanksma PK,Piers DA,Jager PL

更新日期：2003-11-01 00:00:00

abstract：:This study assessed the clinical usefulness of a new technetium-99m labelled somatostatin analogue from the standpoint of oncological diagnostics. The study group comprised 40 patients in whom malignant neoplasms (32 primary and 8 metastatic) had been diagnosed. Among the primary tumours there were 21 cases of lung ca...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Płachcińska A,Mikołajczak R,Maecke HR,Młodkowska E,Kunert-Radek J,Michalski A,Rzeszutek K,Kozak J,Kuśmierek J

更新日期：2003-10-01 00:00:00

abstract：:This study investigated the feasibility of ordered subsets expectation maximisation (OS-EM) reconstruction of 180 degrees pinhole single-photon emission tomography (SPET) acquired in body contour mode (variable distance between the detector and the axis of rotation for each projection) with or without a tilted detecto...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Seret A,Flérès D,Firket O,Defrise M

更新日期：2003-09-01 00:00:00

abstract：:The development of monofunctional DTPA derivatives has been a major breakthrough in the labelling of proteins or peptides with a variety of radiometals. Although this methodology is simple and useful for indium-111 labelling, the stability of these conjugates is too low for most therapeutic nuclides. Cyclic chelators,...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Béhé M,Becker W,Gotthardt M,Angerstein C,Behr TM

更新日期：2003-08-01 00:00:00

abstract：:The aim of this study was to describe the anatomical structures that show uptake of the somatostatin analogue octreotide in patients with thyroid-associated orbitopathy (TAO). The study population comprised a series of 20 TAO patients attending the out-patient thyroid clinic and 12 patients presenting head or neck tum...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kainz H,Bale R,Donnemiller E,Gabriel M,Kovacs P,Decristoforo C,Moncayo R

更新日期：2003-08-01 00:00:00

abstract：:The aim of this study was to evaluate fluorine-18 fluorodeoxyglucose ([(18)F]FDG) imaging of head and neck tumours using a second- or third-generation hybrid PET device. Results were compared with the findings of spiral computed tomography (CT) and magnetic resonance imaging (MRI), and, as regards lymph node metastasi...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Dresel S,Grammerstorff J,Schwenzer K,Brinkbäumer K,Schmid R,Pfluger T,Hahn K

更新日期：2003-07-01 00:00:00

abstract：:Recent developments in stem cell and gene therapy will require methods to monitor stem cell survival and integration repeatedly and non-invasively with a high temporal and spatial resolution in vivo. The aim of this study was to visualise embryonic and neuronal stem cells with standard contrast agents using a conventi...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Rudelius M,Daldrup-Link HE,Heinzmann U,Piontek G,Settles M,Link TM,Schlegel J

更新日期：2003-07-01 00:00:00

abstract：:We evaluated an autoradiographic (ARG) method to calculate regional cerebral blood flow (rCBF) sequentially before and after an acetazolamide (ACZ) challenge in a single session of single-photon emission tomography (SPET) with two injections of N-isopropyl-[(123)I] p-iodoamphetamine (IMP). The method uses a table look...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Nishizawa S,Iida H,Tsuchida T,Ito H,Konishi J,Yonekura Y

更新日期：2003-07-01 00:00:00

abstract：:Both electrocardiographically (ECG) gated blood pool SPET (GBPS) and ECG-gated myocardial perfusion SPET (GSPET) are currently used for the measurement of global systolic left ventricular (LV) function. In this study, we aimed to compare the value of GSPET and GBPS for this purpose. The population included 65 patients...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Daou D,Vilain D,Colin P,Lebtahi R,Fourme T,Coaguila C,Benada A,Idy-Peretti I,Slama M,Le Guludec D

更新日期：2003-06-01 00:00:00

abstract：:We present a system of image co-registration and its validation in phantom and volunteer studies. The system co-registered images via six novel non-invasive and non-radioactive external markers. The fiducial markers were attached with sponge bases on the skin surface of the phantom and the volunteers in a non-collinea...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Wu TH,Wang JK,Lee JJ,Liu RS,Guo WY

更新日期：2003-06-01 00:00:00

abstract：:Positron emission tomography (PET) has now gained a place in the management of patients with cancer, including those with Hodgkin's disease and non-Hodgkin's lymphoma. Restaging studies and those addressing the monitoring of response to treatment are especially in focus. Most of the knowledge gained has been achieved ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Visvikis D,Ell PJ

更新日期：2003-06-01 00:00:00

abstract：:The last 25 years have seen major changes in the imaging investigation and subsequent management of patients with Hodgkin's disease (HD) and non-Hodgkin's lymphoma (NHL); accurate staging is vital for prognostication and treatment in both, and particularly in HD. The choice of imaging modality for staging depends on i...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Vinnicombe SJ,Reznek RH

更新日期：2003-06-01 00:00:00

abstract：:We prospectively studied 43 patients with solitary cold thyroid nodules greater than 1.5 cm in diameter to determine the comparative diagnostic value of radionuclide thyroid angiography (RTA), technetium-99m methoxyisobutylisonitrile ((99m)Tc-MIBI) scintigraphy and power Doppler ultrasonography (PDUS) in the different...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Demirel K,Kapucu O,Yücel C,Ozdemir H,Ayvaz G,Taneri F

更新日期：2003-05-01 00:00:00

abstract：:Hypoxia imparts resistance to radiotherapy and chemotherapy and also promotes a variety of changes in tumor biology through inducible promoters. The purpose of this study was to evaluate the use of positron emission tomography (PET) imaging with fluorine-18 fluoromisonidazole (FMISO) in soft tissue sarcomas (STS) as a...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Rajendran JG,Wilson DC,Conrad EU,Peterson LM,Bruckner JD,Rasey JS,Chin LK,Hofstrand PD,Grierson JR,Eary JF,Krohn KA

更新日期：2003-05-01 00:00:00

abstract：:The aim of this study was to validate the estimation of left ventricular end-diastolic and end-systolic volumes (EDV, ESV) and ejection fraction (LVEF) as well as wall motion analysis from gated fluorine-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) in patients with severe coronary artery disease (CAD...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Schaefer WM,Lipke CS,Nowak B,Kaiser HJ,Buecker A,Krombach GA,Buell U,Kühl HP

更新日期：2003-04-01 00:00:00

abstract：:This study was performed to assess the potential benefit of positron emission tomography (PET) using fluorine-18 fluorodeoxyglucose (FDG) in patients with cervical metastasis of squamous cell carcinoma from an unknown primary tumour. Eighteen patients with cervical metastasis of squamous cell carcinoma from an unknown...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Stoeckli SJ,Mosna-Firlejczyk K,Goerres GW

更新日期：2003-03-01 00:00:00

abstract：:Improvements in the specificity of radiopharmaceutical compounds have been paralleled by an upsurge of interest in developing small detectors to assist surgeons in localizing tumour tissue during surgery. This study reports the main technical features and physical characteristics of a new hand-held gamma camera dedica...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Pitre S,Ménard L,Ricard M,Solal M,Garbay JR,Charon Y

更新日期：2003-03-01 00:00:00

abstract：:Vagus nerve stimulation (VNS) has gained recognition as a treatment for refractory epilepsies where surgical treatment is not possible. While it appears that this treatment is effective in some patients, the mechanism of action is not clearly understood. The purpose of this study was to clarify findings of other posit...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Barnes A,Duncan R,Chisholm JA,Lindsay K,Patterson J,Wyper D

更新日期：2003-02-01 00:00:00